Publications
* Chew EY, Burns SA, Abraham AG, Bakhoum MF, Beckman JA, Chui TYP, Finger RP, Frangi AF, Gottesman RF, Grant MB, Hanssen H, Lee CS, Meyer ML, Rizzoni D, Rudnicka AR, Schuman JS, Seidelmann SB, Tang WHW, Adhikari BB, Danthi N, Hong Y, Reid D, Shen GL and Oh YS. Standardization and clinical applications of retinal imaging biomarkers for cardiovascular disease: a Roadmap from an NHLBI workshop. Nature Reviews Cardiology. 2024. DOI: 10.1038/s41569-024-01060-8
* Bousquet E, Santina A, Au A, Somisetty S, Abraham N, Voichanski S, Estawro R, Fouad YA, Romero-Morales V, Bakhoum MF and Sarraf D. Retinal Ischemic Perivascular Lesions are associated with myocardial infarction in patients with coronary artery disease. American Journal of Ophthalmology. 2024 Aug;264:224-228. DOI: 10.1016/j.ajo.2024.03.017
* Bakhoum CY, Madala S, Lando L, Yarmohammadi A, Long CP, Miguez S, Chan AX, Singer M, Jin A, Steren BJ, Adabifirouzjaei F, Goldbaum MH, DeMaria AN, Sarraf D, Bakhoum MF. Retinal Ischemic Perivascular Lesions (RIPLs) in Individuals with Atrial Fibrillation. Journal of American Heart Association. 2023 Aug 15;12(16):e028853. DOI: 10.1161/JAHA.122.028853
* Demkowicz PC, Pointdujour-Lim R, Miguez S, Lee RY, Jones BSCL, Barker CA, Bosenberg M, Abramson DH, Shoushtari AN, Kluger H, Francis JH, Sznol M and Bakhoum MF. Determinants of Overall Survival in Patients with Metastatic Uveal Melanoma. Cancer. 2023 Jun 29. DOI: 10.1002/cncr.34927
* Agustinus AS, Al-Rawi D, Dameracharla B, Raviram R, Jones BS, Stransky S, Scipioni L, Luebeck J, Di Bona MD, Norkunaite D, Myers RM, Duran M, Choi S, Weigelt B, Yomtoubian S, McPherson A, Toufektchan E, Keuper K, Mischel PS, Mittal V, Shah S, Maciejowski J, Storchova Z, Gratton E, Ly P, Landau D, Bakhoum MF, Koche RP, Sidoli S, Bafna V, David Y, Bakhoum SF. Epigenetic dysregulation from chromosomal transit in micronuclei. Nature. 2023 Jun 7. DOI: 10.1038/s41586-023-06084-7
* Miguez S, Lee RY, Chan AX, Demkowicz PC, Jones BSCL, Long CP, Abramson DH, Bosenberg M, Sznol M, Kluger H, Goldbaum MH, Francis JH, Pointdujour-Lim R, Bakhoum MF. Validation of the Prognostic Usefulness of the Gene Expression Profiling Test in Patients with Uveal Melanoma. Ophthalmology. 2023 Feb 4. DOI: DOI: 10.1016/j.ophtha.2023.01.020
* Madala S, Adabifirouzaej F, Lando L, Yarmohammadi A, Long CP, Bakhoum CY, Goldbaum MH, Sarraf D, DeMaria AN and Bakhoum MF. Retinal Ischemic Perivascular Lesions, a biomarker of cardiovascular disease. Ophthalmology Retina. 2022 May 16;S2468-6530(22)00239-1. DOI: 10.1016/j.oret.2022.05.005
* Bakhoum CY, Madala S, Long CK, Adabifirouzaej F, Freeman WR, Goldbaum MH, DeMaria AN and Bakhoum MF. Retinal vein occlusion is associated with stroke independent of underlying cardiovascular disease. Eye. 2022 Apr 11. DOI: 10.1038/s41433-022-02038-x
* Bakhoum MF, Francis JH, Agustinus A, Earlie EM, Di Bona M, Abramson DH, Duran M, Masilionis I, Molina E, Shoushtari AN, Goldbaum MH, Mischel PS, Bakhoum SF and Laughney AM. Loss of Polycomb Repressive Complex 1 activity and chromosomal instability drive uveal melanoma progression. Nature Communications. 2021. DOI: 10.1038/s41467-021-25529-z
* Bakhoum MF, Curtis EJ, Goldbaum MH and Mischel PS. BAP1 methylation: a prognostic marker of uveal melanoma metastasis. NPJ Precision Oncology. 2021 Sep 5:89. DOI: 10.1038/s41698-021-00226-8
* Long C, Chan AX, Bakhoum CY, Toomey CB, Madala S, Garg AK, Freeman WR, Goldbaum MH, DeMaria AN and Bakhoum MF. Prevalence of subclinical retinal ischemia in cardiovascular disease - a hypothesis driven study. EClinical Medicine. 2021 Mar 2;33:100775. DOI: 10.1016/j.eclinm.2021.100775
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* Melms JC, Biermann J, Huang H, Wang Y, Nair A, Tagore S, Katsyv I, Rendeiro AF, Amin AD, Schapiro D, Frangieh CJ, Luoma AM, Filliol A, Fang Y, Ravichandran H, Clausi MG, Alba GA, Rogava M, Chen SW, Ho P, Montoro D, Guo X, Kornberg AE, Han AS, Bakhoum MF, Anandasabapathy AN, Suarez-Farinas M, Bakhoum SF, Lefkowitch JH, Marboe C, Lagana SM, Del Portillo A, Zorn E, Markowitz GS, Schwabe RF, Schwartz RE, Elemento O, Saqi A, Hibshoosh H, Que J and Izar B. A single-cell lung atlas of lethal COVID-19. Nature. 2021 Apr 29. doi: 10.1038/s41586-021-03569-1
* Chan AX, Ritter M and Bakhoum MF. Bilateral cotton wool spots after ambuxlatory COVID-19. International Journal of Infectious Diseases. 2021 Apr;105:414-415. DOI: 10.1016/j.ijid.2021.02.119
* Bakhoum MF, Ritter M, Garg AK, Chan, AX Bakhoum CY and Smith DM. Subclinical ocular inflammation in persons recovered from ambulatory COVID-19. medRxiv 2020. DOI: 10.1101/2020https://doi.org/10.1101/2020.09.22.20128140.09.22.20128140.
* Chan AX, Bakhoum CY, Bangen K and Bakhoum MF. Relationship between retinal vascular occlusions and cognitive dementia in a large cross-sectional cohort. American Journal of Ophthalmology. 2021 Jan 30;226:201-205. DOI: 10.1016/j.ajo.2021.01.026
* Bakhoum MF, Knight DK and Goldbaum MH. Defining extent and edges of diffuse choroidal melanoma with indocyanine green angiography. Ophthalmology. 2021 Jun;128(6):834. DOI: 10.1016/j.ophtha.2020.12.018
* Long C, Bakhoum MF and Freeman WF. Depigmented Chorioretinal Lesions Following Varicella Zoster Virus Infection. JAMA Ophthalmology. 2020 Nov 1;138(11):e201652. DOI: 10.1001/jamaophthalmol.2020.1652
* Toomey CB, Protopsaltis NJ, Phou S, Bakhoum MF, Thorson JA, Ediriwickrema LS, Korn BS, Kikkawa DO, Goldbaum MH and Lin JH. Prevalence of Mismatch Repair Gene Mutations in Uveal Melanoma. Retina. 2020 Feb 6.
* Bakhoum MF and Esmaeli B. Molecular Characteristics of Uveal Melanoma: Insights from the Cancer Genome Atlas (TCGA) Project. Cancers. 2019 Jul 27;11(8). DOI: 10.3390/cancers11081061
* Bakhoum MF, Freund KB, Dolz-Marco R, Leong BC, Caroline CR, Duker JS and Sarraf D. Paracentral acute middle maculopathy and the ischemic cascade associated with retinal vascular occlusion. American Journal of Ophthalmology. 2018 Aug; (18)30424-0. DOI: 10.1016/j.ajo.2018.07.031
* Bakhoum MF, Wu WP, White EC, Sengillo JD, Sanfilippo C, Morcos MM, Freund KB, Perry HD, Sarraf D and Tsang SH. Mitochondrial A3243G mutation results in Corneal Endothelial Polymegathism. Graefe's Archive for Clinical and Experimental Ophthalmology. 2018 Mar;256(3):583-588. DOI: 10.1007/s00417-018-3914-z
* White EC, Sengillo JD, Cho GY, Bakhoum MF and Tsang SH. Congenital grouped albinotic spots of the retinal pigment epithelium in a patient with hemihypertrophy and café au lait spots. Doc Ophthalmol. 2018 May 16.
* Apatoff MBL, Sengillo JD, White EC, Bakhoum MF, Bassuk AG, Mahajan VB, Tsang SH. Autologous Stem Cell Therapy for Inherited and Acquired Retinal Disease. Regenerative Medicine. 2018 Jan;13(1):89-96
* Bakhoum MF, Sengillo JD and Tsang SH. Autoimmune retinopathy in a patient with a missense mutation in PITPNM3. Retin Cases Brief Rep. 2017 Nov 22.
* Sengillo JD, Lee W, Bakhoum MF, Cho GY, Chiang J and Tsang SH. Choroideremia Associated with a Novel Synonymous Mutation in Gene Encoding REP-1. Retin Cases Brief Rep. 2017 Oct 17.
* Bakhoum MF, Alexander JM and Perry HD. A pseudopupil - Anterior iris stroma hyperplasia. Ophthalmology. 2017 Jun;124(6):775.
* Chao D, Bakhoum MF and Esmaeli B. “Ophthalmic Emergencies in Cancer Patients”. IN Todd KH and Thomas CR (eds): Oncologic Emergency Medicine. Principles and Practice. Springer (2016).
* El-Sawy T, Bakhoum MF, Tetzlaff M, Nasser QJ, Prieto VG, Ivan D, Sniegowski M, Yin V, Pan C, Durairaj V and Esmaeli B. Primary Orbital Melanoma in Association with Cellular Blue Nevus. Digit J Ophthalmol. 2014 July 14;20(3)
* Merrit H, Bakhoum MF, Sniegowski MC and Esmaeli B. A 66 year Old Woman with Extensive Conjunctival Melanosis. Digit J Ophthalmol. 2014 May 8;20(2):32-4
* Sniegowski MC, Roberts D, Bakhoum M, Mc Laughlin P, Yin VT, Turturro F, and Esmaeli B. Ocular adnexal lymphoma: validation of American Joint Committee on Cancer seventh edition staging guidelines. Br J Ophthalmology 2014 Sep;98(9):1255-60
* Bakhoum MF, Bakhoum CY, Ding Z, Carlton SM, Campbell G, and Jackson GR. Evidence for Autophagic Gridlock in Aging and Neurodegeneration. Translational Research. 2014 Jul;164(1):1-12. DOI: 10.1016/j.trsl.2014.01.016
* Choksi DK, Roy B, Chatterjee S, Yusuff T, Bakhoum MF, Sengupta U, Ambegaokar S, Kayed R and Jackson GR. TDP-43 Phosphorylation by Casein Kinase Iepsilon Promotes Oligomerization and Enhances Toxicity In Vivo. Human Molecular Genetics. (2013) Nov 18
* Nasser QJ, Pfeiffer ML, Romaguera J, Fowler N, Debnam JM, Samaniego F, El Sawy T, McLaughlin P, Bakhoum MF and Esmaeli B. Clinical Value of Magnetic Resonance Imaging and Other Baseline Testing for Conjunctival Mucosa-Associated Lymphoid Tissue Lymphoma. Leukemia and Lymphoma. (2013) Aug 28
* Phirke P, Efimenko E, Mohan S, Burghoorn J, Crona F, Bakhoum MW, Trieb M, Schuske K, Jorgensen EM, Piasecki BP, Leroux MR, Swoboda P. Transcriptional profiling of C. elegans DAF-19 uncovers a ciliary base-associated protein and a CDK/CCRK/LF2p-related kinase required for intraflagellar transport. Dev Biol. (2011) Sep 1;357(1):235-47.
* Bakhoum MF and Jackson GR. Demise of the flies why Drosophila models still matter. Prog Mol Biol Transl Sci (2011) vol. 100 pp. 483-98. DOI: 10.1016/B978-0-12-384878-9.00011-X
* Chen N, Mah A, Blacque OE, Chu J, Phgora K, Bakhoum MW, Newbury CR, Khattra J, Chan S, Go A, Efimenko E, Johnsen R, Phirke P, Swoboda P, Marra M, Moerman DG, Leroux MR, Baillie DL, Stein LD. Identification of ciliary and ciliopathy genes in Caenorhabditis elegans through comparative genomics. Genome Biol (2006) 7(12):R126.